Yes, it should work with any type of midi input . Download it and give it a go.The only issue is whether there is a delay between playing a note and the midi note event being transmitted (the latency). Does your Midi Guitar setup have low latency?
I am interested to know what is your Midi Guitar setup? How are you converting the notes you play on the guitar into midi events?
I am planning a new version soon that may have a fix for the latency issue so that may not be a problem.